One-step isolation and activation with flexible active release to optimize T cell phenotype

App Notes & White Papers Cell therapy Manufacturing & scale-up Manufacturing automation
Research and clinical outcomes have established that delivering a higher-quality pool of early T cell phenotypes is key to improving the reliability and longevity of therapeutic outcomes. To aid in the production of the desired phenotypes, the Gibco™ CTS™ Detachable Dynabeads™ CD3/CD28 Kit (active-release beads) was developed. The kit builds on the one-step isolation and activation using the CTS Dynabeads CD3/CD28 beads (passive-release beads) and provides control of activation with user-defined dissociation of the active-release beads at any time after activation. This feature was designed to help preserve an early T cell phenotype and shorten the T cell manufacturing process to a few days.
This content was supplied by Thermo Fisher Scientific.

Application Note CTS Detachable Dynabeads CD3-CD28 Kit provides one-step isolation and activation with flexible active release to optimize T cell phenotype August 2023 (1)