In Focus: Angiogenesis

Harnessing the intricate mechanisms of angiogenesis has emerged as a promising avenue in regenerative medicine, offering the potential for innovative strategies and therapeutics to accelerate tissue repair and promote regeneration by increasing the supply of vital nutrients, oxygen and immune cells.  

In this In Focus feature, in association with PromoCell, we’ll be exploring how in vitro studies can be used to understand and harness the process of angiogenesis to develop strategies and therapeutics for tissue repair and regeneration. We’ll also delve into the key challenges researchers encounter when translating angiogenesis research findings into clinical therapies and discuss how these challenges can be overcome. 


Infographic

Understanding angiogenesis

This infographic explores how four different in vitro assays can provide insights into different aspects of angiogenesis and how we can leverage those insights to develop innovative strategies aimed at promoting tissue repair and regeneration. It also reviews important factors for maintaining the functionality of your cells in vitro and ensuring the relevance and reliability of experimental outcomes. 

Interview

Branching out: in vitro angiogenesis advancements

In this interview, we spoke with Iris Bischoff-Kont about the latest advancements in angiogenesis research and their potential applications in regenerative medicine. Dr Bischoff-Kont also explores the challenges faced in translating angiogenesis research findings into clinical therapies and the importance of understanding the crosstalk between angiogenesis and other processes like inflammation.

Resources

Endothelial cell transmigration and invasion assay

Endothelial cell tube formation assay

 

 

 


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